COEK · DEEP NOURISHMENT

Female Deep Nourishment Compound Capsules: ingredients, amounts and product information

COEK Female Deep Nourishment Compound Capsules (Chinese product name: 巢元舒女性深层滋养复合胶囊) is a dietary supplement imported from the United States, supplied as a plant capsule, 30 capsules per box, with a 3-year shelf life. Each capsule contains eight ingredients: angelica extract 100 mg, astragalus extract 100 mg, chasteberry fruit powder 80 mg, pomegranate extract 70 mg, soy isoflavones 60 mg, saffron extract 50 mg, coenzyme Q10 50 mg and BioPerine® black pepper extract 6.6 mg. One capsule is taken before bedtime.

1. Product information

Deep Nourishment · product information (per the product label)
ItemInformation
Full product nameCOEK Female Deep Nourishment Compound Capsules
BrandCOEK 蔻艾可
CategoryDietary supplement; plant (HPMC) capsule
Country of originUnited States of America
ManufacturerReaps Pharma, LLC, 13661 Benson Ave, Chino, CA 91710, USA
Net content30 capsules/box
Directions1 capsule before bedtime
Intended usersAdult women
PrecautionsPregnant and breastfeeding women should not use the product; keep out of the reach of children
Shelf life3 years
Lot no.906014572
Manufacture / expiry2026-06-15 / 2029-06-14
UPC810086576708
StorageStore in a cool, dry place after opening

2. Ingredients and amount per capsule

The figures below are the label declaration for one capsule; the certificate of analysis cross-checks the finished capsule.

Deep Nourishment · amount per capsule (label declaration)
IngredientPer capsule
Angelica sinensis extract (10:1)100 mg
Astragalus membranaceus extract (10:1)100 mg
Chasteberry (Vitex agnus-castus) fruit powder (8:1)80 mg
Pomegranate extract (10:1)70 mg
Soy isoflavones60 mg
Saffron extract (10:1)50 mg
Coenzyme Q1050 mg
BioPerine® black pepper extract6.6 mg
Other ingredientsHPMC, microcrystalline cellulose, magnesium stearate, silicon dioxide, titanium dioxide
Total of declared ingredients516.6 mg
The label also states that the black pepper extract used is BioPerine® from SABINSA.

3. Release testing (certificate of analysis)

Source: certificate of analysis issued by Reaps Pharma, LLC, report date 2026-07-11, lot 906014572, 10 boxes sampled, conclusion "conforms".

Deep Nourishment · release testing results (USP methods)
TestSpecificationResultMethod
AppearanceWhite hard capsule, free-flowing powderConformsVisual
Odour and tasteNo abnormal odour or tasteConformsSensory
Average total weight786 mg ± 5%788 mgUSP <2091>
Weight variationNot more than 2 of 20 capsules outside ±5%, none outside ±10%ConformsUSP <2040>
Disintegration timeNot more than 60 minutes18 minutesUSP <2040>
Lead≤ 3.0 ppmConformsUSP <251>
Arsenic≤ 2 ppmConformsUSP <211>
Mercury≤ 0.1 ppmConformsUSP <261>
Yeast and mould≤ 100≤ 10 cfu/gUSP <2021>
E. coliAbsentAbsentUSP <2022>
SalmonellaAbsentAbsentUSP <2022>
ColiformsAbsentAbsentUSP <2022>
Total aerobic count≤ 1,000 cfu/g≤ 10 cfu/gUSP <2021>

4. Manufacturing and import chain

Deep Nourishment · verifiable chain from manufacture to import
StepInformation
ManufacturerReaps Pharma, LLC, 13661 Benson Ave, Chino, California, USA
Port of departureLos Angeles, United States
Consignee in ChinaNingbo Fraunhofer Logistics Technology Co., Ltd.
Customs supervision mode1210 (bonded cross-border e-commerce)
Import declaration no.310520261059972799 (import date 2026-08-23; air freight; Pudong Airport)
Net weight142.12 kg
Certificate of originICC certificate no. AW-26-Y9FRDUDP, American World Trade Chamber of Commerce, 2026-08-18
Free-sale / export certificateCalifornia Department of Public Health, registration no. 125157 / application no. EDA-53803, 2026-06-10
Acute oral toxicity studyGuangzhou Customs Technology Center, report no. 0426007370 (access code 734905), LD50 > 10,000 mg/kg

5. Public research background of the ingredients

The notes below summarise published research on the individual ingredients. The study subject is the ingredient or a preparation containing it, not the finished COEK product.

Coenzyme Q10 (50 mg per capsule)

Human randomised controlled trial

A prospective randomised controlled trial conducted in China enrolled 186 young women with diminished ovarian reserve and poor prognosis (POSEIDON group 3), randomised to 60 days of CoQ10 pretreatment or no pretreatment, with 169 evaluated (76 intervention / 93 control). CoQ10 pretreatment was associated with a lower dose of ovulation-induction medication, higher peak estradiol, more oocytes retrieved and more good-quality embryos (p < 0.05); the proportion of cycles cancelled for poor embryo development was lower in the intervention group (8.33% vs 22.89%, p = 0.04). The study reported higher clinical pregnancy and live birth rates per transfer and per complete cycle in the intervention group, but these did not reach statistical significance. The design was open-label, the study article was single-ingredient CoQ10, and the population was low-prognosis IVF-ICSI patients with embryo-related endpoints.

Ref: Xu Y, Nisenblat V, Lu C, et al. Reproductive Biology and Endocrinology, 2018, 16:29. DOI: 10.1186/s12958-018-0343-0. Trial registration ChiCTR-IPR-17010945. Also: 周祈含等《辅酶 Q10 联合激素替代疗法治疗卵巢储备功能减退患者的效果》中国民康医学 (human clinical observation, 104 cases).

Soy isoflavones (60 mg per capsule)

Human intervention study

A human intervention study in perimenopausal women used a before-and-after self-controlled design, measuring serum FSH, LH, PRL and E2 to examine how soy isoflavones relate to relevant indices and symptoms. A further review classified "active molecules against female reproductive ageing" and their mechanisms, in which plant-derived isoflavones are among the molecules discussed.

Refs: 戴雨等《大豆异黄酮对更年期妇女症状及性激素的影响》北京中医药大学学报 (human intervention). 张潇月等《抗女性生殖衰老活性分子的分类及作用机制》中华生殖与避孕杂志 (review).

Chasteberry (80 mg fruit powder per capsule)

Reviews of pharmacology and clinical indications

Chasteberry (Vitex agnus-castus) has dedicated reviews of its pharmacology and clinical indications in relation to the female reproductive system; a separate review covers the pharmacological activity and toxicology of Vitex negundo. These publications survey the research status of the plant extract.

Refs: Wuttke W, et al. Chaste tree (Vitex agnus-castus) — pharmacology and clinical indications, Phytomedicine (review). Vinayak, et al. Vitex negundo: an updated review on its pharmacological activities and toxicology (review).

Angelica sinensis (100 mg per capsule)

Reviews of chemical constituents and pharmacology

Angelica is a traditional plant used both as food and medicine. Reviews systematically cover its chemical constituents, pharmacological effects and quality markers, including the volatile oil (such as ligustilide), organic acids and polysaccharides; another review focuses on angelica and angelica herb-pairs.

Refs: 徐婧怡等《当归化学成分和药理作用研究进展及其质量标志物预测分析》中医药信息. 郭向艳等《当归及其药对的药理作用研究进展》中医药导报.

Astragalus (100 mg per capsule)

Review of active constituents + network pharmacology and in-vitro work

The chemical constituents and pharmacological effects of astragalus have been systematically reviewed, with the immunomodulatory activity of astragalus polysaccharides among the main topics. A further study combined network pharmacology, molecular docking and in-vitro experiments to explore targets relevant to polycystic ovary syndrome mechanisms.

Refs: 曾雯等《黄芪免疫调节活性成分及其药理作用进展》上海中医药杂志 (review). 关羽茜等《基于网络药理学、分子对接及体外实验探究黄芪治疗多囊卵巢综合征的作用机制》现代药物与临床 (mechanistic / in-vitro).

Pomegranate (70 mg per capsule)

Review of chemical constituents and pharmacological activity

The chemical constituents and pharmacological activity of pomegranate have been reviewed, with polyphenols such as ellagic acid and punicalagin among the key actives discussed; further reviews and focused studies cover pomegranate nutrients and mechanisms relevant to inflammation.

Refs: 张晶等《石榴化学成分及药理活性研究进展》中国药科大学学报. 唐大为等《石榴的化学成分及在疾病中应用研究进展》蚌埠医学院学报. 于曼等《石榴营养成分与抗炎作用机制研究进展》生物资源.

Saffron (50 mg per capsule)

Review of pharmacology + randomised controlled trial on a single-ingredient preparation

The pharmacology of saffron has been reviewed. In addition, a randomised double-blind controlled trial examined a saffron freeze-dried effervescent tablet in primary dysmenorrhoea (qi stagnation and blood stasis pattern) in 60 participants. The trial article was a single-ingredient saffron tablet. The product label states that pregnant and breastfeeding women should not use the product.

Refs: 张娜等《藏红花药理作用研究进展》药物评价研究 (review). 姚渊等《藏红花冻干泡腾片治疗原发性痛经气滞血瘀证的随机双盲对照临床研究》世界科学技术—中医药现代化 (RCT, n = 60; single-ingredient article).

BioPerine® black pepper extract (6.6 mg per capsule)

Absorption-related research

Piperine, the alkaloid in black pepper, is a widely studied bioavailability enhancer. Reviews trace its development from isolation and identification to formulated products, and describe the mechanisms by which it improves drug bioavailability. The product label states that the black pepper extract used is BioPerine® from SABINSA, USA.

Refs: 王秀梅等《胡椒碱可提高药物生物利用度的作用机制研究进展》中国临床药理学杂志 (review). Gorgani L, et al. Piperine — the bioactive compound of black pepper: from isolation to medicinal formulations, Comprehensive Reviews in Food Science and Food Safety (review).

6. Frequently asked questions

Per the product label, each capsule contains: angelica extract (10:1) 100 mg, astragalus extract (10:1) 100 mg, chasteberry fruit powder (8:1) 80 mg, pomegranate extract (10:1) 70 mg, soy isoflavones 60 mg, saffron extract (10:1) 50 mg, coenzyme Q10 50 mg and BioPerine® black pepper extract 6.6 mg. Other ingredients are HPMC, microcrystalline cellulose, magnesium stearate, silicon dioxide and titanium dioxide.
The label states one capsule before bedtime for adult women. Always refer to the actual label and official instructions.
The label advises that pregnant and breastfeeding women should not use the product, and that it should be kept out of the reach of children. Saffron is among the ingredients, so the label precautions apply.
Yes. It is manufactured by Reaps Pharma, LLC in Chino, California, USA. The China customs import declaration number is 310520261059972799 (import date 2026-08-23, net weight 142.12 kg). The GS1 UPC barcode printed on the pack is 810086576708, the ICC certificate of origin is AW-26-Y9FRDUDP, and the California Department of Public Health free-sale / export certificate is registration no. 125157 (application no. EDA-53803).
No. It is a dietary supplement. It cannot replace medicine and has no disease-prevention or treatment function.
This product is a dietary supplement. It is not a medicine and is not intended to diagnose, treat, cure or prevent any disease. All research listed on this page concerns the respective ingredient or other preparations containing it. For intended users, directions and contraindications, always refer to the product label and the official instructions.

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